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Table 2 Clinicopathological parameters of formalin-fixed paraffin-embedded breast cancer specimens (n = 150)

From: Frequent loss of endothelin-3 (EDN3) expression due to epigenetic inactivation in human breast cancer

Variables Numbera Percentage
Clinicopathological factors   
   Age at diagnosisb   
≤ 59 years 83 55.3
> 59 years 67 44.7
   Tumour sizec   
pT1 48 32.0
pT2 71 47.3
pT3 9 6.0
pT4 20 13.3
pTx 2 1.3
   Lymph node statusc   
pN0 67 44.7
pN1 35 23.3
pN2 25 16.7
pN3 20 13.3
pNx 3 2.0
   Histological grade   
G1 13 8.7
G2 70 46.7
G3 66 44.0
NA 1 0.7
   Histological type   
Ductal 122 81.3
Lobular 12 18.0
Other 16 10.7
   Tumour focality   
Unifocal 130 86.7
Multifocal 19 12.7
NA 1 0.7
Immunohistochemistry   
   Oestrogen receptor   
Negative (IRSd ≤ 2) 38 25.3
Positive (IRS > 2) 83 55.3
NA 29 19.3
   Progesterone receptor   
Negative (IRSd ≤ 2) 85 56.7
Positive (IRS > 2) 40 26.7
NA 25 16.7
   Her2 status   
Negative (DAKO score 0; 1+) 105 70.0
Positive (DAKO score 2+; 3+) 23 15.3
NA 22 14.7
  1. Due to rounding, percentages may not sum to 100. aOnly female patients with primary invasive breast cancer were included. bMedian 59 years, range 29 to 82 years. cAccording to the UICC (Union Internationale contre le Cancer): TNM Classification of Malignant Tumours [19]. dImmunoreactivity score (IRS) according to Remmele and Stegner [24]. NA, information not available.