|
HER2
|
pHER1
|
pHER2
|
pHER3
|
HER4
|
pErk
|
---|
|
(-)
|
(+)
|
(-)
|
(+)
|
(-)
|
Weak
|
Strong
|
(-)
|
(+)
|
Low
|
High
|
(-)
|
Moderate
|
Strong
|
---|
pHER1
| | | | | | | | | | | | | | |
Negative
|
202
|
15
| | | | | | | | | | | | |
Positive
|
40
|
7
| | | | | | | | | | | | |
P value
|
0.083
| | | | | | | | | | | | |
pHER2
| | | | | | | | | | | | | | |
Negative
|
154
|
1
|
148
|
7
| | | | | | | | | | |
Weak
|
65
|
6
|
55
|
15
| | | | | | | | | | |
Strong
|
23
|
15
|
13
|
25
| | | | | | | | | | |
P value
|
<0.0001 (+)
|
<0.0001 (+)
| | | | | | | | | | |
pHER3
| | | | | | | | | | | | | | |
Negative
|
211
|
10
|
199
|
21
|
144
|
61
|
14
| | | | | | | |
Positive
|
28
|
12
|
13
|
26
|
6
|
10
|
24
| | | | | | | |
P value
|
<0.0001 (+)
|
<0.0001 (+)
|
<0.0001 (+)
| | | | | | | | |
HER4
| | | | | | | | | | | | | | |
Low
|
75
|
10
|
69
|
16
|
49
|
16
|
19
|
71
|
13
| | | | | |
High
|
163
|
12
|
142
|
31
|
102
|
53
|
19
|
145
|
27
| | | | | |
P value
|
0.234
|
0.865
|
0.021 (-)
| |
1.000
| | | | | |
pErk
| | | | | | | | | | | | | | |
Negative
|
103
|
10
|
97
|
16
|
70
|
25
|
17
|
99
|
12
|
44
|
65
| | | |
Moderate
|
56
|
5
|
47
|
14
|
31
|
21
|
9
|
52
|
9
|
17
|
42
| | | |
Strong
|
75
|
7
|
65
|
15
|
46
|
24
|
11
|
64
|
17
|
22
|
60
| | | |
P value
|
1.000
|
0.328
|
0.495
|
0.146
|
0.073
| | | |
pAkt
| | | | | | | | | | | | | | |
Negative
|
66
|
4
|
63
|
7
|
55
|
9
|
6
|
64
|
4
|
28
|
39
|
48
|
15
|
7
|
Moderate
|
99
|
7
|
88
|
17
|
58
|
30
|
17
|
87
|
17
|
34
|
71
|
40
|
22
|
37
|
Strong
|
74
|
11
|
64
|
21
|
40
|
30
|
15
|
66
|
18
|
21
|
62
|
23
|
22
|
37
|
P value
|
0.213
|
0.057
|
0.002 (+)
|
0.021(+)
|
0.102
|
<0.0001 (+)
|
- Fisher's exact test was used to obtain the P values. (+) and (-), positive and negative correlations. Bold data represent significant values.