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Table 1 Clinicopathological parameters

From: Determination of HER2 phosphorylation at tyrosine 1221/1222 improves prediction of poor survival for breast cancer patients with hormone receptor-positive tumors

Parameter

n

%

World Health Organization diagnosis

  

   Invasive ductal

230

86

   Invasive lobular

32

12

   Ductal with ductal carcinoma in situ

2

1

   Unknown

4

1

   Total

268

 

Tumor grade

  

   1

62

27

   2

103

45

   3

63

28

   Total

228

 

Tumor size

  

   <2 cm

85

32

   2 to 5 cm

161

60

   >5 cm

22

8

   Total

268

 

Nodal status

  

   0

22

8

   1 to 3

149

56

   ≥4

97

36

   Total

268

 

Receptor status (estrogen receptor or progesterone receptor)

  

   Negative

1

0

   Positive

267

100

   Total

268

 

HER2

  

   Negative

246

92

   Positive

22

8

   Total

268

 

Recurrence

  

   No

179

67

   Yes

89

33

   Total

268

 

Death

  

   No

146

54

   Yes

122

46

   Total

268

 
  1. Tumor grade was scored according to Bloom and Richardson. HER2 was analyzed by standard testing (that is, the HercepTest™), followed by fluorescence in situ hybridization analysis of the cases scoring 2+.