Table 2 Characteristics of the study sample

Age on index date (years):

   55 to 64

2,116 (38)

21,160 (38)

   65 to 74

1,800 (32)

18,000 (32)

   75 to 84

1,356 (24)

13,560 (24)

   ≥ 85

293 (5.3)

2,930 (5.3)

Medical history, n (%):

   Congestive heart failure

160 (2.9)

1,337 (2.4)

   Atrial fibrillation/flutter

224 (4.0)

1,819 (3.3)

   Prediagnosis mammography^a

< 1 year:

417 (81)

84 (1.6)

1 to < 2 years:

3 (0.6)

84 (1.6)

2 to < 3 years:

9 (1.7)

84 (1.6)

≥ 3 years:

17 (3.3)

130 (2.5)

   Myocardial infarction

123 (2.2)

1,492 (2.7)

   Chronic pulmonary disease

334 (6.0)

3,125 (5.6)

   Peripheral vascular disease

167 (3.0)

1,563 (2.8)

   Cerebrovascular disease

275 (4.9)

2,842 (5.1)

   Lymphoma

12 (0.2)

155 (0.3)

   Other solid tumor

0

0

   Liver disease

44 (0.8)

403 (0.7)

   Diabetes (type I or II)

215 (3.9)

1,706 (3.1)

   Diabetes with end-organ complication

85 (1.5)

591 (1.1)

   Renal disease

35 (0.6)

446 (0.8)

Other drug exposures, n (%):

   Hormone replacement therapy

2,062 (37)

17,582 (32)

   Anticoagulants

231 (4.2)

2,109 (3.8)

   NSAIDs

3,106 (56)

29,964 (54)

   Aspirin, low-dose (< 150 mg)

205 (3.7)

2,004 (3.6)

   Aspirin, high-dose (≥ 150 mg)

505 (9.1)

4,878 (8.8)