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Figure 1 | Breast Cancer Research

Figure 1

From: Redefining prognostic factors for breast cancer: YB-1 is a stronger predictor of relapse and disease-specific survival than estrogen receptor or HER-2 across all tumor subtypes

Figure 1

YB-1 expression is associated with relapse and poor survival in the entire cohort. (a) Out of a total of 1,201 patients, YB-1 was expressed in 41% (495/1201) with recurrent breast cancer. YB-1 expression was associated with shorter relapse free survival. 'N' represents the number of patients who had breast cancer recurrence (number of events). (b) The expression of YB-1 is associated with a significant increase in breast cancer specific deaths (BCSS). YB-1 was expressed in 35% (1,081/3,097) of patients with reduced BCSS. Patient survival was based on deaths specifically related to breast cancer and not other causes. BCSS = breast cancer specific survival; YB-1 = Y-box binding protein-1.

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Breast Cancer Research

ISSN: 1465-542X

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