Table 5 Hazard ratios of dying from breast cancer in relation to use of menopausal hormone therapy

Never use

230/1,491

1.9

1.0 (reference)

1.0 (reference)

Current use^d

46/477

1.1

0.55 (0.40 to 0.77)

0.63 (0.42 to 0.95)

   By duration

<5 years

28/216

1.5

0.73 (0.48 to 1.13)

0.76 (0.45 to 1.27)

≥ 5 years

18/260

0.8

0.42 (0.26 to 0.68)

0.52 (0.29 to 0.93)

   By regimen

Estrogen^-progestin

37/391

1.1

0.54 (0.37 to 0.77)

0.59 (0.38 to 0.91)

Estrogen alone

8/80

1.1

0.59 (0.29 to 1.20)

0.78 (0.34 to 1.80)

Past use^e

34/219

1.9

1.01 (0.71 to 1.45)

1.03 (0.68 to 1.54)

   By duration

<5 years

25/155

1.9

1.04 (0.69 to 1.58)

1.02 (0.64 to 1.63)

≥ 5 years

9/64

1.7

0.94 (0.48 to 1.83)

1.02 (0.48 to 2.17)