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Table 2 Distribution of background, tumor characteristics, and recent mammography in relation to use of menopausal hormone therapy

From: Menopausal hormone therapy in relation to breast cancer characteristics and prognosis: a cohort study

 

Never use

Past use

Current use

Missing

Total

1,788

253

523

96

Age at diagnosis

    

   50 to 54 years

154 (9)

23 (9)

148 (28)

20

   55 to 59 years

320 (18)

45 (18)

181 (35)

32

   60 to 64 years

381 (21)

54 (21)

116 (22)

19

   65 to 69 years

521 (29)

70 (28)

55 (11)

15

   70 to 74 years

412 (23)

61 (24)

23 (4)

10

   P valuea

 

0.99

<0.0001

 

Socioeconomic statusb

    

   Low

961 (54)

120 (47)

197 (38)

57

   High

811 (46)

133 (53)

325 (62)

39

   Missing

16

0

1

0

   P valuea

 

0.042

<0.0001

 

Recent mammography

    

   Yes

933 (59)

147 (64)

361 (73)

61

   No

650 (41)

83 (36)

133 (27)

29

   Missing

205

23

29

6

   P valuea

 

0.15

<0.0001

 

Tumor size

    

   ≤ 10 mm

488 (28)

59 (24)

151 (29)

30

   11 to 20 mm

759 (43)

115 (46)

240 (46)

39

   21 to 50 mm

471 (27)

72 (29)

120 (23)

26

   >50 mm

56 (3)

3 (1)

10 (2)

1

   Missing

14

4

2

0

   P valuea

 

0.17

0.15

 

Lymph node involvement

    

   0 lymph nodes

1,164 (68)

164 (67)

353 (69)

69

   1 to 3 lymph nodes

362 (21)

53 (22)

113 (22)

18

   >3 lymph nodes

187 (11)

29 (12)

46 (9)

7

   Missing

75

7

11

2

   P valuea

 

0.90

0.44

 

Mean number of examined lymph nodes

10.4

10.8

10.7

 

Grade

    

   1

164 (14)

17 (10)

78 (23)

13

   2

524 (43)

65 (40)

133 (39)

20

   3

520 (43)

81 (50)

130 (38)

33

   Missing

580

90

182

30

   P valuea

 

0.23

0.0002

 

Histology

    

   Ductal

1,314 (74)

180 (72)

338 (66)

69

   Lobular

186 (11)

31 (12)

81 (16)

11

   Other

269 (15)

38 (15)

93 (18)

15

   Missing

19

4

11

1

   P valuea

 

0.64

0.0004

 

Estrogen receptor (ER), progesterone receptor (PR) status

    

   ER-PR-

227 (18)

37 (19)

55 (15)

17

   ER+PR-

200 (16)

32 (17)

40 (11)

14

   ER-PR+

42 (3)

5 (3)

23 (6)

2

   ER+PR+

776 (62)

116 (61)

240 (67)

40

   Missing

543

63

165

23

   P valuea

 

0.91

0.0044

 
  1. Data presented as n (%). Past use, last use at least 6 months before diagnosis; current use, last use <6 months before diagnosis. aTwo-sided global chi-squared P value for past use and current use, respectively, compared with no use of menopausal hormone therapy. bLow level includes blue-collar workers and low-level white-collar workers, whereas high level includes all other categories.