Figure 2
From: ERalpha-status of disseminated tumour cells in bone marrow of primary breast cancer patients
Typical cytomorphology (nuclear size clearly enlarged, high nuclear to cytoplasmic ratio) and immunophenotype (irregular cytoplasmic staining for cytokeratin, cytokeratin filaments can be seen) of a representative disseminated tumour cell from a breast cancer patient. The tumour cell is stained with an anti-cytokeratin-fluorescein isothiocyanate (green) (×40 oil immersion objective).