Table 2 Association of ISG15 immunoreactivity with clinical and pathological characteristics assessed in clinical routine examination of the validation set
Characteristic | Low ISG15(Score 0 to 3) | High ISG15(Score 4 to 12) | Total n (%) | p-value | |
|---|---|---|---|---|---|
Total | 333 (51.5) | 313 (48.5) | 646 (100) | n/a | |
Age ( t -test) | Mean (± SD) | 57.3(± 12.2) | 59.2 (± 12.4) | 58.2 (± 12.3) | 0.053 |
Total | 333 | 313 | 646 | ||
Age | < 50 | 91 (52.3) | 83 (47.7) | 174 (100) | 0.05 |
50–59 | 108 (59.3) | 74 (40.7) | 182 (100) | ||
60–69 | 80 (45.7) | 95 (54.3) | 175 (100) | ||
≥ 70 | 54 (47.0) | 61 (53.0) | 115 (100) | ||
total | 333 (51.5) | 313 (48.5) | 646 (100) | ||
pT a | pT1 | 185 (56.9) | 140 (43.1) | 325 (100) | 0.006 |
PT2 to 4 | 139 (45.9) | 164 (54.1) | 303 (100) | ||
Total | 324 (51.6) | 304 (48.4) | 628 (100) | ||
pN a | pN0 | 193 (52.9) | 172 (47.1) | 365 (100) | 0.504 |
pN1 | 134 (50.2) | 133 (49.8) | 267 (100) | ||
Total | 327 (51.7) | 305 (48.3) | 632 (100) | ||
Grading | 1 or 2 | 240 (55.0) | 196 (45.0) | 436 (100) | 0.007 |
3 | 90 (43.7) | 116 (56.3) | 206 (100) | ||
Total | 330 (51.4) | 312 (48.6) | 642 (100) | ||
Hormone receptor Status | Negative | 54 (43.2) | 71 (56.8) | 125 (100) | 0.177 |
Positive | 234 (50.0) | 234 (50.0) | 468 (100) | ||
Total | 288 (48.6) | 305 (51.4) | 593 (100) |