Figure 4

Expression profiles were determined using cDNA dot-blot hybridisation analysis (BD Clontech) containing cDNA pairs derived from 50 matched normal breast tissues (N), tumourous breast tissues (T) and three lymph node metastastic tissues (marked with arrows). Upregulation of ISG15 was observed in primary breast tumours and in one of three metastatic lymph nodes, as compared with matched normal breast tissue.