Skip to main content

Table 1 SEARCH participant survival characteristics

From: Effects of common germline genetic variation in cell cycle control genes on breast cancer survival: results from a population-based cohort

  Set 1 Sets 1 and 2
  n = 2,270 n = 4,470
Total time at risk, years 1,3851.47   2,5049.24  
Median follow-up, yearsa 7.75 (0.56–10)b 7.45 (0.48–10)b
Median time at risk, years 6.47 (0.10–9.64)b 5.70 (0.03–9.77)b
Median time from diagnosis to study entry, years 0.73 (0.00–8.64)b 1.16 (0.00–9.34)b
Number of deaths 359   637  
Annual mortality rate 0.026   0.025  
5-year survival rate 0.88 (0.86–0.89)c 0.88 (0.87–0.89)c
Median age at diagnosis, years 50.2 (25–69)b 51.0 (23–69)b
Age at diagnosis, years     
   <40 212 9.30% 394 8.81%
   40–49 753 33.20% 1,331 29.78%
   50–59 997 43.90% 1,802 40.31%
   60+ 308 13.60% 943 21.10%
Histopathological grade     
   Well differentiated 434 19.11% 871 19.49%
   Moderately differentiated 787 34.67% 1,687 37.74%
   Poorly differentiated 504 22.20% 1,019 22.80%
   Unknown 545 24.00% 893 19.98%
Morphological type     
   Ductal 1,674 73.74% 3,316 74.18%
   Lobular 351 15.46% 659 14.74%
   Other 222 9.78% 455 10.17%
   Unknown 23 1.01% 40 0.89%
Clinical stage     
   1 1,112 48.99% 2,190 48.99%
   2 986 43.33% 1,981 44.32%
   3 or 4 172 7.58% 194 4.34%
   Missing 0 0% 105 2.35%
  1. aFollow-up censored at 10 years. bRange of variable. c95% confidence interval. SEARCH, Studies of Epidemiology and Risk factors in Cancer Heredity.