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Table 5 Comparison of primary tumor gene methylation status relative to patient menopausal status

From: Estrogen receptor and HER2/neu status affect epigenetic differences of tumor-related genes in primary breast tumors

Gene

Premenopause (n = 70)

Postmenopause (n = 60)

P valuea

 

n

%

n

%

 

RASSF1A

52

74%

44

73%

NS

CCND2

40

57%

31

52%

NS

GSTP1

13

19%

10

17%

NS

TWIST

25

36%

24

40%

NS

APC

27

39%

24

40%

NS

  1. aχ2 test. NS, not significant.