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Table 3 Predictive power of multimarker panels

From: Serum biomarker profiles and response to neoadjuvant chemotherapy for locally advanced breast cancer

Panel Timepoint Response type Sensitivity (%) Specificity (%)
α-Fetoprotein, soluble vascular cell adhesion molecule 1, MMP-9 Pretreatment Clinical complete response versus no response 83 91
Tissue plasminogen activator inhibitor 1 Pretreatment Clinical complete response/clinical partial response versus no response 75 77
MMP-3, luteinizing hormone, thyroid-stimulating hormone Pre-cycle 2 Clinical complete response versus no response 82 73
ErbB2, epidermal growth factor receptor, migration inhibitory factor, MMP-2, CD40 ligand Pre-cycle 2 Pathologic complete response/pathologic partial response versus no response 85 69