From: Serum biomarker profiles and response to neoadjuvant chemotherapy for locally advanced breast cancer
Biomarker category | Individual biomarkers |
---|---|
Cancer antigens/oncogenes | α-Fetoprotein, CA 125, CA 19-9, CA 15-3, CA 72-4, carcinoembryonic antigen |
Cytokines/chemokines/receptors | Eotaxin, fractalkine, granulocyte–macrophage colony-stimulating factor, IFNγ, IL-10, IL-12p70, IL-13, IL-1β, IL-1Rα, IL-2, IL-2R, IL-4, IL-5, IL-6, IL-6R, IL-7, IL-8, IP-10, migration inhibitory factor, MIP-1β, soluble CD40L, TNFα, TNF-R1, TNF-R2 |
Growth/angiogenic factors | Epidermal growth factor receptor, ErbB2, insulin-like growth factor binding protein 1, transforming growth factor alpha |
Proteases | Kallikrein 10, MMP-2, MMP-3, MMP-9 |
Hormones | Adrenocorticotropic hormone, follicle-stimulating hormone, growth hormone, luteinizing hormone, prolactin, thyroid-stimulating hormone |
Adipokines | Adiponectin |
Apoptosis-related molecules | Cyfra 21-1, DR5, soluble Fas, soluble Fas ligand |
Metastasis-related molecules | Myeloperoxidase, tissue plasminogen activator inhibitor 1 |
Adhesion molecules | Soluble intracellular adhesion molecule 1, soluble vascular cell adhesion molecule 1 |
Other proteins | HE4, mesothelin |