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Table 1 Characteristics of the breast cancer case – control sample in the European Prospective into Cancer-Norfolk cohort

From: Breast cancer risk in relation to urinary and serum biomarkers of phytoestrogen exposure in the European Prospective into Cancer-Norfolk cohort study

 

Cases (n = 237)

Controls (n = 952)

P valuea

Age (years)

58.5 (8.6)

58.7 (8.9)

0.791

Weight (kg)

69.2 (11.4)

67.7 (11.2)

0.068

Energy intake (kcal/day)

1745.9 (386.6)

1678.6 (385.2)

0.022

Fat intake (g/day)

66.5 (19.7)

63.5 (20.1)

0.038

Alcohol intake (g/day)

8.6 (12.1)

7.8 (11.2)

0.179

Oestradiol (pmol/l)b

173.1 (341.3)

136.9 (259.4)

0.066

Age at menarche (years)

12.8 (1.6)

13.0 (1.5)

0.058

Family history of breast cancer: yes

23 (10%)

74 (8%)

0.216

Breastfed children: yes

155 (65%)

617 (65%)

0.865

Number of children

   

   0

38 (16%)

117 (12%)

0.174

   1

26 (11%)

134 (14%)

 

   2

103 (43%)

398 (42%)

 

   3

57 (24%)

218 (23%)

 

   4+

13 (6%)

85 (9%)

 

Menopausal statusc

   

   Premenopausal

28 (12%)

123 (13%)

0.569

   Perimenopausal

15 (6%)

51 (5%)

 

   Postmenopausal 1

57 (24%)

195 (21%)

 

   Postmenopausal 2

137 (58%)

583 (61%)

 

Menopausal hormone therapy use

   

   Current

63 (27%)

207 (22%)

0.256

   Former

30 (13%)

118 (12%)

 

   Never

144 (61%)

627 (66%)

 

Oral contraceptive use

   

   Current

9 (4%)

13 (1%)

0.041

   Former

98 (41%)

419 (44%)

 

   Never

130 (55%)

520 (55%)

 

Social class

   

   Professional/manager

105 (45%)

405 (42%)

0.620

   Skilled nonmanual

46 (20%)

171 (18%)

 

   Skilled manual

51 (22%)

197 (21%)

 

   Semi-skilled/nonskilled

20 (9%)

112 (12%)

 

   Missing/unclassified

15 (4%)

67 (7%)

 

Smoking status

   

   Current

26 (11%)

94 (10%)

0.822

   Former

70 (30%)

297 (32%)

 

   Never

137 (59%)

550 (59%)

 
  1. Data presented as mean ± standard deviation or n (column percentage). a P values obtained with a t test for continuous values and a chi-square test for categorical variables. bOestradiol data availability: serum phytoestrogens, 153 cases and 603 controls (51 cases and 185 controls among the oestrogen receptor-positive subgroup); urinary phytoestrogens, 141 cases and 543 controls (49 cases and 171 controls among the oestrogen receptor subgroup). cPerimenopausal, <1 year since last menstrual cycle; postmenopausal 1, 2 to 5 years since last menstrual cycle; postmenopausal 2, 5 years or more since last menstrual cycle.