Skip to main content

Table 3 Effect of a subsequent pregnancy on outcome in breast cancer survivors

From: Cancer and fertility preservation: fertility preservation in breast cancer patients

Reference Year Patients (n) Controls (n) Relative risk (95% confidence interval) of recurrence or death/% recurrence Outcome
Ariel and Kempner [62] 1989 47   30% recurrence No adverse effect on survival
Sutton and colleagues [63] 1990 23 204 28% recurrence, 3 deaths No adverse effect on survival
Sankila and colleagues [64] 1994 91 471 0.20 (0.10 to 0.50) No adverse effect on survival
von Schoultz and colleagues [65] 1995 50 2,119 0.48 (0.18 to 1.29) No adverse effect on survival
Malamos and colleagues [66] 1996 21 222 14.3% recurrence No adverse effect on survival
Kroman and colleagues [67] 1997 173 5,514 0.55 (0.28 to 1.06) Decreased risk in pregnant women
Velentgas and colleagues [68] 1999 3 265 0.80 (0.30 to 2.30) No adverse effect on survival
Gelber and colleagues [69] 2001 94 94 0.44 (0.21 to 0.46) Decreased risk in pregnant women
Müller and colleagues [70] 2003 438 2,775 0.54 (0.41 to 0.71) Decreased risk in pregnant women
Blakely and colleagues [71] 2004 47 323 0.70 (0.25 to 1.95) No adverse effect on survival
Ives and colleagues [72] 2007 123 2,416 0.59 (0.37 to 0.95) Decreased risk in pregnant women
Total   1,110 14,164