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Table 6 Multivariate logistic regression analysis of established and experimental factors for predicting a clinical response after two cycles, irrespective of study treatment

From: Clinical response after two cycles compared to HER2, Ki-67, p53, and bcl-2 in independently predicting a pathological complete response after preoperative chemotherapy in patients with operable carcinoma of the breast

 

Odds ratio

95% CI

p Value

Menopausal status

1.35

0.72 to 2.55

0.351

Tumour size

0.93

0.49 to 1.75

0.821

Clinical nodal status

1.04

0.56 to 1.94

0.903

Grade

0.67

0.33 to 1.38

0.279

ER

1.09

0.43 to 2.77

0.850

PgR

0.56

0.23 to 1.35

0.195

Ki-67

0.58

0.29 to 1.15

0.120

HER2

0.99

0.46 to 2.16

0.990

p53

1.43

0.69 to 2.96

0.338

bcl-2

2.75

1.27 to 5.97

0.011

  1. ER, oestrogen receptor; HER2, human epidermal growth factor receptor 2; PgR, progesterone receptor.