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Table 6 Multivariate logistic regression analysis of established and experimental factors for predicting a clinical response after two cycles, irrespective of study treatment

From: Clinical response after two cycles compared to HER2, Ki-67, p53, and bcl-2 in independently predicting a pathological complete response after preoperative chemotherapy in patients with operable carcinoma of the breast

  Odds ratio 95% CI p Value
Menopausal status 1.35 0.72 to 2.55 0.351
Tumour size 0.93 0.49 to 1.75 0.821
Clinical nodal status 1.04 0.56 to 1.94 0.903
Grade 0.67 0.33 to 1.38 0.279
ER 1.09 0.43 to 2.77 0.850
PgR 0.56 0.23 to 1.35 0.195
Ki-67 0.58 0.29 to 1.15 0.120
HER2 0.99 0.46 to 2.16 0.990
p53 1.43 0.69 to 2.96 0.338
bcl-2 2.75 1.27 to 5.97 0.011
  1. ER, oestrogen receptor; HER2, human epidermal growth factor receptor 2; PgR, progesterone receptor.