Table 3 Results of Cox regression analysis of survival predictors in 126 patients with BM.

ER- and PR- vs ER or PR+

1.477 (1.006–2.168)

0.047

1.656 (1.107–2.478)

0.014*

HER2- vs HER2+

1.625 (1.125–2.347)

0.010

1.608 (1.099–2.352)

0.014*

Triple negative vs others

1.758 (1.194–2.588)

0.004

1.692 (1.137–2.518)

0.010*

Age ≥ 45 yrs vs < 45 yrs

1.815 (1.245–2.647)

0.002

1.700 (1.155–2.504)

0.007†

Disease free interval: < 24 months vs ≥ 24 months

1.857 (1.258–2.740)

0.002

1.379 (0.897–2.119)

0.143†

Interval from recurrence to BM: < 12 months vs ≥ 12 months

0.688 (0.478–0.988)

0.043

0.702 (0.478–1.031)

0.071†

Number of metastatic sites: ≥ 3 vs < 3

1.710 (1.155–2.532)

0.007

1.769 (1.141–2.743)

0.011†

Leptomeningeal disease: presence vs absence

2.069 (1.153–3.713)

0.015

2.865 (1.506–5.450)

0.001†