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Table 5 Multivariate analysis of relapse-free survival in the test set for all eight tissue microarray biomarkers

From: Can clinically relevant prognostic subsets of breast cancer patients with four or more involved axillary lymph nodes be identified through immunohistochemical biomarkers? A tissue microarray feasibility study

Biomarker

HR (95% CI)

P

ER

0.87 (0.55–1.38)

0.5

PR

0.58 (0.39–0.86)

0.006

HER2

0.93 (0.61–1.42)

0.7

EGFR

1.20 (0.63–2.29)

0.6

Ki-67

1.99 (1.32–3.00)

0.001

p53

0.88 (0.58–1.35)

0.6

CA IX

1.67 (1.06–2.64)

0.03

CK5/6

0.81 (0.43–1.54)

0.5

  1. ER, estrogen receptor; PR, progesterone receptor; HER2, human epidermal growth factor receptor 2; EGFR, human epidermal growth factor receptor 1; CA IX, carbonic anhydrase IX; CK5/6, cytokeratin 5/6; HR, hazard ratio for positive expression status for that marker; CI, confidence interval.
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Breast Cancer Research

ISSN: 1465-542X

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