Table 2 Univariate analysis of relapse-free survival for conventional prognostic factors in the test set cohort

Overall

313

5.2 (3.9–6.5)

Age

313

≤40

34

2.9 (1.3–4.5)

1

>40

279

5.6 (4.2–7.0)

0.74 (0.48–1.13)

0.2

Menopausal status

307

Pre

104

3.7 (2.1–5.2)

1

Post

203

6.0 (3.9–8.2)

0.79 (0.59–1.05)

0.1

Tumor grade

297

1, 2

5, 101

9.5 (4.9–14.2)

1

3

191

4.0 (3.3–4.8)

1.24 (1.06–1.45)

0.007

Tumor size, cm

308

0 to 2

100

11.0

1

>2 to 5

173

4.5 (3.5–5.6)

1.67 (1.21–2.33)

0.002

>5

35

3.0 (0–6.2)

1.55 (0.95–2.54)

0.08

Pathological ER status^a

306

Negative

72

2.0 (0.9–3.0)

1

Positive

234

6.8 (4.0–9.5)

0.53 (0.38–0.72)

0.00007

Lymphovascular invasion

293

Negative

49

12.0 (5.3–18.8)

1

Positive

244

4.5 (3.5–5.4)

1.73 (1.13–2.66)

0.01

Percentage of positive nodes

313

0–50

121

9.2 (5.7–12.8)

1

>50–99

142

4.8 (3.5–6.2)

1.52 (1.11–2.09)

0.01

100%

50

3.1 (1.8–4.4)

1.96 (1.30–2.94)

0.001

Number of positive nodes

313

4–9

235

5.3 (3.9–6.7)

1

≥10

78

4.8 (2.1–7.6)

1.16 (0.85–1.60)

0.4

Histology

313

Ductal

279

5.1 (3.8–6.5)

1

Lobular

34

6.4 (2.7–10.1)

1.16 (0.76–1.77)

0.5