Figure 10
From: Silencing of GM3 synthase suppresses lung metastasis of murine breast cancer cells
Effects of PI3K/Akt signal on the anchorage-independent growth of breast cancer cells. The anchorage-independent growth of both GM3S-knockdown 4T1 cells and the mock transfected 4T1 cells (5 × 103 cells/well) were not affected by the inhibition of the PI3K/AKT pathway. CMP, cytidine 5'-monophosphate; GM3S, CMP-N-acetylneuraminic acid:lactosylceramide 2,3-sialyltransferase; PI3K, phosphoinositide-3 kinase.