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Table 3 Summary of diet effects on leptin and apoptosis signaling protein and mRNA expression levels

From: Effects of high-fat diet and/or body weight on mammary tumor leptin and apoptosis signaling pathways in MMTV-TGF-α mice

  MT MFP
Leptin signaling molecules     
   Leptin NC NC NC
   ObR NC NC
   ObRb
   Jak2 NM NM
   pSTAT3 NC NC
Apoptosis signaling molecules     
   PARP (total)    
   PARP (89 kDa)   NC  
   PARP (24 kDa)   NC  
   Caspase-3 activity    
   Bax NC    
   Bcl-2 NC   NC  
   Bcl-XL    
   pAkt NC   NC  
  1. Jak2, Janus kinase 2; MFP, mammary fat pad; MT, mammary tumor; NC, no statistically significant change; NM, not measured; pAkt, phosphorylated Akt; PARP, poly(ADP-ribose)polymerase; pSTAT3, phosphorylated signal transducer and activator of transcription 3. Solid arrows show protein expression and dashed lines mRNA expression.