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Table 4 Univariate analysis of nuclear and cytoplasmic factor-inhibiting hypoxia-inducible factor 1 (FIH-1) expression with hypoxia-inducible factor 1α (HIF-1α) expression

From: Cytoplasmic location of factor-inhibiting hypoxia-inducible factor is associated with an enhanced hypoxic response and a shorter survival in invasive breast cancer

  Nuclear FIH-1-positive (n = 186) Nuclear FIH-1-negative (n = 109) P value Cytoplasmic FIH-1-positive (n = 197) Cytoplasmic FIH-1-negative (n = 98) P value
Nuclear HIF-1α    0.004    0.93
   Negative 52 48   66 32  
   Positive 114 50   110 52  
Cytoplasmic HIF-1α    0.68    0.03
   Negative 129 72   130 68  
   Positive 33 21   43 10  
  1. n < 295 data not available.