Table 4 Univariate analysis of nuclear and cytoplasmic factor-inhibiting hypoxia-inducible factor 1 (FIH-1) expression with hypoxia-inducible factor 1α (HIF-1α) expression
| Nuclear FIH-1-positive (n = 186) | Nuclear FIH-1-negative (n = 109) | P value | Cytoplasmic FIH-1-positive (n = 197) | Cytoplasmic FIH-1-negative (n = 98) | P value | |
|---|---|---|---|---|---|---|
| Nuclear HIF-1α | 0.004 | 0.93 | ||||
| Negative | 52 | 48 | 66 | 32 | ||
| Positive | 114 | 50 | 110 | 52 | ||
| Cytoplasmic HIF-1α | 0.68 | 0.03 | ||||
| Negative | 129 | 72 | 130 | 68 | ||
| Positive | 33 | 21 | 43 | 10 |