Figure 2From: Intrinsic genetic characteristics determine tumor-modifying capacity of fibroblasts: matrix metalloproteinase-3 5A/5A genotype enhances breast cancer cell invasionReproducibility of invasion assays. Conditioned media (CM) and fibroblast co-culture invasion assays with the MDA MB 468 breast cancer cell line were carried out in triplicate on three separate days. A high level of reproducibility was obtained between experiments. The two different types of assay demonstrate significantly different levels of invasion, with higher tumor invasion in the presence of fibroblasts compared with CM alone (p = 0.001).Back to article page