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Table 1 YB-1 is highly expressed in triple negative breast cancer

From: Epidermal growth factor receptor (EGFR) is transcriptionally induced by the Y-box binding protein-1 (YB-1) and can be inhibited with Iressa in basal-like breast cancer, providing a potential target for therapy

Marker

Correlation

Likelihood ratio value

YB-1

P = 3.899 × 10-4

12.58

 

N = 27/37 (73%)

 

EGFR

P = 9.206 × 10-12

46.491

 

N = 20/37 (57.1%)

 
  1. Y-box binding protein 1 (YB-1) is expressed in 73% of triple negative breast cancers in the TMA438. Epidermal growth factor receptor (EGFR) is expressed in 57.1% of these cases.
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Breast Cancer Research

ISSN: 1465-542X

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