Table 5 Fluorescence in situ hybridisation studies comparing primary breast cancers and their matched distant metastases
From: HER2gene status in primary breast cancers and matched distant metastases
Reference | n | Discordance between metastases and primary tumours (percentage) | Number of HER2-positive primary tumours | Number of HER2-positive metastases |
|---|---|---|---|---|
[23] | 12 | 0 | 12 | 12 |
[20] | 68 | 7.0 | 2 | 3 |
[22] | 14 | 0 | 14 | 14 |
[21] | 18 | 22.2 | 3 | 7 |
[19] | 17 | 6.0 | Not available | Not available |
This study | 105 | 7.6 | 21 | 20 |