Table 2 Spearman correlation coefficients (P values) between cord blood sex hormones, growth factors, and associated binding proteins and cord blood hematopoietic progenitor/stem cell populations
Hormone/binding protein | Total nucleated cells/ml | Mononuclear cells/ml | Measures of stem cell potential, counts/103 mononuclear cells | |||
|---|---|---|---|---|---|---|
|  |  |  | CD34+ (n = 289) | CD34+CD38- (n = 289) | CD34+c-kit + (n = 249)a | Granulocyte–macrophage colony-forming units (n = 175)b |
Estradiol | 0.14 (0.02) | 0.15 (0.01) | 0.05 (0.37) | 0.02 (0.79) | 0.06 (0.36) | 0.03 (0.67) |
Estriol | 0.20 (0.0006) | 0.15 (0.01) | 0.09 (0.14) | 0.14 (0.02) | 0.15 (0.02) | 0.11 (0.16) |
Testosterone | 0.19 (0.001) | 0.13 (0.03) | -0.03 (0.60) | 0.01 (0.80) | 0.02 (0.80) | 0.06 (0.41) |
Sex hormone-binding globulin | 0.003 (0.96) | 0.05 (0.36) | -0.12 (0.04) | -0.13 (0.03) | -0.13 (0.03) | -0.16 (0.04) |
Progesterone | 0.15 (0.009) | 0.15 (0.01) | -0.01 (0.84) | -0.04 (0.50) | -0.008 (0.90) | -0.009 (0.91) |
Prolactin | 0.27 (<0.0001) | 0.21 (0.0004) | -0.005 (0.93) | 0.02 (0.70) | 0.09 (0.17) | 0.01 (0.90) |
Insulin-like growth factor-1 | -0.05 (0.41) | -0.09 (0.14) | 0.18 (0.002) | 0.19 (0.001) | 0.21 (0.001) | 0.18 (0.02) |
Insulin-like growth factor binding protein-3 | 0.10 (0.10) | 0.08 (0.20) | 0.14 (0.01) | 0.11 (0.07) | 0.12 (0.05) | 0.11 (0.14) |