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Table 2 Spearman correlation coefficients (P values) between cord blood sex hormones, growth factors, and associated binding proteins and cord blood hematopoietic progenitor/stem cell populations

From: Correlation of umbilical cord blood hormones and growth factors with stem cell potential: implications for the prenatal origin of breast cancer hypothesis

Hormone/binding protein Total nucleated cells/ml Mononuclear cells/ml Measures of stem cell potential, counts/103 mononuclear cells
    CD34+ (n = 289) CD34+CD38- (n = 289) CD34+c-kit + (n = 249)a Granulocyte–macrophage colony-forming units (n = 175)b
Estradiol 0.14 (0.02) 0.15 (0.01) 0.05 (0.37) 0.02 (0.79) 0.06 (0.36) 0.03 (0.67)
Estriol 0.20 (0.0006) 0.15 (0.01) 0.09 (0.14) 0.14 (0.02) 0.15 (0.02) 0.11 (0.16)
Testosterone 0.19 (0.001) 0.13 (0.03) -0.03 (0.60) 0.01 (0.80) 0.02 (0.80) 0.06 (0.41)
Sex hormone-binding globulin 0.003 (0.96) 0.05 (0.36) -0.12 (0.04) -0.13 (0.03) -0.13 (0.03) -0.16 (0.04)
Progesterone 0.15 (0.009) 0.15 (0.01) -0.01 (0.84) -0.04 (0.50) -0.008 (0.90) -0.009 (0.91)
Prolactin 0.27 (<0.0001) 0.21 (0.0004) -0.005 (0.93) 0.02 (0.70) 0.09 (0.17) 0.01 (0.90)
Insulin-like growth factor-1 -0.05 (0.41) -0.09 (0.14) 0.18 (0.002) 0.19 (0.001) 0.21 (0.001) 0.18 (0.02)
Insulin-like growth factor binding protein-3 0.10 (0.10) 0.08 (0.20) 0.14 (0.01) 0.11 (0.07) 0.12 (0.05) 0.11 (0.14)
  1. aDetermined only in the Tufts–New England Medical Center-derived samples. bData only from the Tufts–New England Medical Center-derived samples.