SNP

Genotype

n

Mean percentage MD^{a}

p for trend^{b}


15

G/G

120

26.4

0.39


A/G

452

27.3
 

A/A

548

26.2
 
16

A/A

36

24.0

0.41


A/G

377

28.0
 

G/G

707

26.3
 
17

G/G

56

25.3

0.75


C/G

405

26.9
 

C/C

635

26.5
 
18

A/A

1

11.9

0.18


A/G

59

23.8
 

G/G

1,060

26.9
 
19

A/A

158

28.4

0.006


G/A

543

27.3
 

G/G

409

24.8
 
20

T/T

5

21.7

0.06


C/T

97

23.6
 

C/C

1,017

27.0
 
21

G/G

120

28.2

0.81


A/G

502

25.6
 

A/A

465

27.3
 
22

T/T

108

28.1

0.44


C/T

441

27.1
 

C/C

557

26.3
 
23

T/T

35

28.2

0.67


C/T

336

26.9
 

C/C

715

26.5
 
24

A/A

195

24.8

0.55


A/G

517

27.4
 

G/G

378

26.5
 
25

C/C

148

25.5

0.86


G/C

511

27.0
 

G/G

383

26.3
 
26

T/T

202

26.4

0.87


T/G

605

26.2
 

G/G

282

26.5
 
27

T/T

49

23.4

0.80


T/G

362

27.4
 

G/G

673

26.4
 
28

A/A

47

27.6

0.65


T/A

359

26.2
 

T/T

700

26.9
 
29

C/C

44

24.0

0.16


T/C

346

26.2
 

T/T

706

27.1
 
 IGFBP, insulinlike growth factor binding protein. ^{a}Multivariateadjusted models including age (continuous), body mass index (continuous), alcohol consumption (category), age at first birth/parity, history of benign breast disease (yes/no), family history of breast cancer (yes/no), menopausal status/postmenopausal hormone use (premenopausal, postmenopausal never user, postmenopausal current user, postmenopausal past user); ^{b}
p for trend based on inclusion of genotype as an ordinal variable in models with squareroottransformed mammographic density as the dependent variable. The result in bold is significant (p ≤ 0.05).