Table 4 AR exon 1 CAG Repeat length and family history in the NHS and the WHS
Family history | Genotypea [CAG]n | 1990–1996 OR (95% CI)b | 1998–2000 OR (95% CI)b | WHS OR (95% CI)b | NHS and WHS Combined OR (95% CI)b |
|---|---|---|---|---|---|
no | <22 | 1.0 (Ref.) | 1.0 (Ref.) | 1.0 (Ref.) | 1.0 (Ref.) |
no | ≥22 | 0.9 (0.8 to 1.2) | 1.0 (0.7 to 1.4) | 0.7 (0.5 to 1.0) | 1.0 (0.9 to 1.2) |
yes | <22 | 1.0 (0.6 to 1.7) | 2.0 (0.9 to 4.2) | 1.6 (0.8 to 3.0) | 1.1 (0.9 to 1.5) |
yes | ≥22 | 1.7 (1.2 to 2.4) | 1.6 (0.9 to 2.6) | 1.1 (0.7 to 1.8) | 1.3 (1.1 to 1.6) |
no | <22 | 1.0 (Ref.) | 1.0 (Ref.) | 1.0 (Ref.) | 1.0 (Ref.) |
no | ≥23 | 0.9 (0.7 to1.2) | 0.9 (0.7 to 1.3) | 0.7 (0.5 to 1.0) | 1.0 (0.9 to 1.2) |
yes | <22 | 1.0 (0.8 to 1.4) | 1.9 (0.9 to 4.1) | 1.6 (0.8 to 3.0) | 1.1 (0.9 to 1.5) |
yes | ≥23 | 1.8 (1.2 to 2.5) | 1.5 (0.9 to 2.6) | 1.0 (0.6 to 1.5) | 1.4 (1.1 to 1.8) |
no | <22 | 1.00 (Ref.) | 1.0 (Ref.) | 1.0 (Ref.) | 1.0 (Ref.) |
no | ≥25 | 1.0 (0.8 to 1.4) | 0.9 (0.6 to 1.3) | 0.7 (0.5 to 1.1) | 1.0 (0.9 to 1.2) |
yes | <22 | 1.1 (0.6 to 1.8) | 1.8 (0.9 to 4.0) | 1.6 (0.8 to 3.0) | 1.1 (0.9 to 1.5) |
yes | ≥25 | 2.0 (1.3 to 3.1) | 1.5 (0.7 to 3.0) | 0.7 (0.4 to 1.3) | 1.5 (1.1 to 2.0) |
no | <22 | 1.0 (Ref.) | 1.0 (Ref.) | 1.0 (Ref.) | 1.0 (Ref.) |
no | ≥27 | 1.1 (0.7 to 1.7) | 1.4 (0.8 to 2.5) | 0.8 (0.5 to 1.3) | 1.1 (0.9 to 1.4) |
yes | <22 | 1.1 (0.6 to 1.9) | 2.0 (0.9 to 4.6) | 1.6 (0.8 to 3.0) | 1.1 (0.9 to 1.6) |
yes | ≥27 | 1.6 (0.8 to 3.1) | 2.1 (0.7 to 6.5) | 0.7 (0.3 to 1.8) | 1.4 (0.9 to 2.1) |