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Table 4 Prognostic factors in 73 invasive ductal carcinomas compared with post-relapse survival

From: p53 protein accumulation predicts resistance to endocrine therapy and decreased post-relapse survival in metastatic breast cancer

  Univariate Multivariate
  P RR 95% CI P RR 95% CI
Age 0.67 0.882 0.494–1.576    
Tumour size 0.21 1.483 0.797–2.759    
Lymph node status 0.40 0.746 0.376–1.479    
Histological grade 0.15 0.500 0.197–1.271    
ER-α 0.0009a 0.342 0.181–0.645 0.79 1.174 0.354–3.886
PR 0.0012a 0.358 0.192–0.668 0.045a 0.291 0.087–0.972
HER2 0.0024a 3.637 1.582–8.362 0.0046a 3.710 1.498–9.191
p53 0.0002a 3.371 1.765–6.440 0.013a 2.364 1.198–4.665
Ki67 0.16 1.539 0.849–2.790    
  1. a P < 0.05 is considered significant. CI, confidence interval; ER, estrogen receptor; PR, progesterone receptor; RR, relative risk.