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Figure 1 | Breast Cancer Research

Figure 1

From: The mTOR inhibitor rapamycin down-regulates the expression of the ubiquitin ligase subunit Skp2 in breast cancer cells

Figure 1

Effect of rapamycin on cell growth. (a) The dose-effect curve of rapamycin on cell growth. The breast cancer cell lines T47D and MDA-MB-231 were treated with different concentrations of rapamycin for 72 h and the decrease in growth rate compared to control cells was assessed. (b) Time dependence of the effect of rapamycin on cell growth. The breast cancer cell lines T47D (left) and MDA-MB-231 (right) were treated with rapamycin (20 nM) for different time periods and the decrease in growth rate compared to control cells was assessed. Results are means ± standard error of the mean, with n = 3 for each treatment. *p < 0.05 between the two conditions.

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