The effect of the stromal component of breast tumours on prediction of clinical outcome using gene expression microarray analysis

Table 3 Misclassification error estimates (leave-one-out cross-validation) for response prediction.

Set of samples	Sample size	Minimum error rate	n of genes used in predictor	p value on 'subset' permutation	p value on 'label' permutation
All (20%–90%)	43	28%	3	Not determined	0.079
High range (50%–95%)	25	12%	4	0.026	0.021
Low range (20%–50%)	24	13%	7	0.039	0.028
Mid range (35%–60%)	24	8%	7	0.001	0.002

Column 1 shows the division of samples into three groups according to percentage invasive tumour content. Details of minimum error predictors for all samples and subsets. Permutation p values were calculated as described in Materials and methods.

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