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Table 2 SAM (significance analysis of microarrays) analysis of genes correlated to percentage tumour content.

From: The effect of the stromal component of breast tumours on prediction of clinical outcome using gene expression microarray analysis

Gene name

Genbank accession

Unigene cluster ID

Symbol

Score (d)

q-value (%)

ADP-ribosylation factor 1

AK023803

Hs.286221

ARF1

3.11

4.13

CDC28 protein kinase regulatory subunit 2

BQ898943

Hs.83758

CKS2

2.73

4.13

TRK-fused gene

NM_006070

Hs.446568

TFG

2.65

4.13

Discs, large homolog 7 (Drosophila)

NM_014750

Hs.77695

DLG7

2.60

4.13

RAB6B, member RAS oncogene family

NM_016577

Hs.352530

RAB6B

2.59

4.13

Epithelial cell transforming sequence 2 oncogene

AY376439

Hs.293257

ECT2

2.56

4.13

FXYD domain containing ion transport regulator 2

CR627143

Hs.413137

FXYD2

2.54

4.13

Ubiquitin specific protease 9, X-linked (fat facets-like, Drosophila)

NM_004652

Hs.77578

USP9X

2.48

4.13

Pitrilysin metalloproteinase 1

CR749279

Hs.528300

PITRM1

2.46

4.13

Myeloid differentiation primary response gene (88)

AK124685

Hs.82116

MYD88

2.44

4.13

Baculoviral IAP repeat-containing 5 (survivin)

NM_001012271

Hs.1578

BIRC5

2.42

4.13

Polo-like kinase 4 (Drosophila)

NM_014264

Hs.172052

PLK4

2.40

4.13

2',3'-cyclic nucleotide 3' phosphodiesterase

NM_033133

Hs.443836

CNP

2.40

4.13

Triosephosphate isomerase 1

BM913099

Hs.83848

TPI1

2.39

4.13

ALL1-fused gene from chromosome 1q

BX649117

Hs.75823

AF1Q

2.37

4.13

Latent transforming growth factor beta binding protein 2

NM_000428

Hs.105689

LTBP2

-3.49

1.00

LIM domain binding 2

AL832772

Hs.4980

LDB2

-3.43

1.00

Collagen, type XV, alpha 1

NM_001855

Hs.409034

COL15A1

-3.39

1.00

Cadherin 5, type 2, VE-cadherin (vascular epithelium)

NM_001795

Hs.76206

CDH5

-3.39

1.00

Forkhead box O1A (rhabdomyosarcoma)

NM_002015

Hs.170133

FOXO1A

-3.17

1.00

TEK tyrosine kinase, endothelial (venous malformations, multiple cutaneous)

BC035514

Hs.89640

TEK

-3.02

1.00

Regulator of G-protein signaling 5

NM_003617

Hs.24950

RGS5

-2.97

1.00

Fasciculation and elongation protein zeta 1 (zygin I)

NM_022549

Hs.79226

FEZ1

-2.90

1.00

Vascular endothelial growth factor C

NM_005429

Hs.79141

VEGFC

-2.90

1.00

Tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain

NM_003841

Hs.253829

TNFRSF10C

-2.82

1.00

CDNA FLJ25106 fis, clone CBR01467

AK128814

Hs.432914

 

-2.79

1.00

Alpha-2-macroglobulin

CR749334

Hs.74561

A2M

-2.77

1.00

Meis1, myeloid ecotropic viral integration site 1 homolog 2 (mouse)

NM_170677

Hs.362805

MEIS2

-2.71

1.00

Tropomodulin 1

AK096156

Hs.404289

TMOD1

-2.70

1.00

Isoleucine-tRNA synthetase

NM_013417

Hs.172801

IARS

-2.63

1.00

  1. Positive values for score (bold) indicate positive correlation with percentage tumour, and negative values indicate inverse correlation with percentage tumour (underlined). The table has been truncated to show only genes with the lowest false discovery rates (q).