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Volume 8 Supplement 1

Symposium Mammographicum 2006

Imaging methods in differentiation between inflammatory breast cancer and post-treatment changes

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The aim of the study is assessment of the role of non-invasive imaging methods such as mammography, ultrasound and magnetic resonance imaging in the diagnosis of inflammatory breast diseases. The study is mainly focused on the pitfalls in the diagnosis of inflammatory breast cancer and differentiation against another inflammatory lesions, including breast tissue changes after radiation therapy. Inflammatory breast cancer has a mammographic pattern of inflammatory changes, such as skin thickening and stromal coarsening and/or diffusely increased breast density with or without an associated mass and/or malignant-type microcalcifications. Ultrasound is helpful not only in depiction of masses masked by the edema pattern, but also in the demonstration of skin and pectoral muscle invasion and axillary involvement. Magnetic resonance imaging is used to differentiate residual tumor from post-treatment fibrosis and glandular tissue.

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    Günhan-Bilgen I, et al: Inflammatory breast carcinoma: mam-mographic, ultrasonographic, clinical, and pathologic findings in 142 cases. Radiology. 2002, 223: 829-838.

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    Hance KW, et al: Trends in inflammatory breast carcinoma incidence and survival: the Surveillance, Epidemiology, and End Results Program at the National Cancer Institute. J Natl Cancer Institute. 2005, 97: 966-975.

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    Morakkabati N, et al: Breast MR imaging during or soon after radiation therapy. Radiology. 2003, 229: 893-901.

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Lehotska, V., Ivanova, S. Imaging methods in differentiation between inflammatory breast cancer and post-treatment changes. Breast Cancer Res 8, P64 (2006) doi:10.1186/bcr1479

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Keywords

  • Breast Cancer
  • Magnetic Resonance Imaging
  • Breast Tissue
  • Residual Tumor
  • Inflammatory Change