Skip to main content

Volume 8 Supplement 1

Symposium Mammographicum 2006

Dominance and nondominance of the radial scar/complex sclerosing lesion and associated pathology

Aim

To establish whether there is a significant difference in the pathology associated with radial scars (RS) or complex sclerosing lesions (CSL).

Patients and methods

RS or CSL were recorded in 178 specimens over a 17-year period. Three associated pathologies were noted – atypical hyperplasia, in situ malignancy and invasive carcinoma. The sclerosing lesions were categorised as to whether the RS/CSL was dominant (i.e. larger than the associated pathology) or nondominant (smaller than the associated pathology).

Results

Sixty-four patients (36%) had RS/CSL with associated pathology: atypical hyperplasia (17), in situ (24) or invasive (23) malignancy. There was a significant (P < 0.001, chi-square 17.5) difference in proportions for histological types between lesions where the RS/CSL was dominant and lesions where they were not. Lesions with a dominant RS/CSL were associated with significantly more in situ malignancy and atypical hyperplasia. Invasive carcinoma was associated with nondominant RS/CSL.

Conclusion

The nature of the associated pathology appears to be related to the dominance or nondominance of the RS/CSL.

Table 1 Table 1

Author information

Affiliations

Authors

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Birchley, D., Steel, J., Jones, P. et al. Dominance and nondominance of the radial scar/complex sclerosing lesion and associated pathology. Breast Cancer Res 8, P8 (2006). https://doi.org/10.1186/bcr1423

Download citation

Keywords

  • Carcinoma
  • Cancer Research
  • Histological Type
  • Invasive Carcinoma
  • Atypical Hyperplasia