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Table 2 Comparison of H4.77.16 and HFR1 staining patterns in the membrane, cytoplasm and nucleus

From: HER4 in breast cancer: comparison of antibodies against intra- and extra-cellular domains of HER4

  

H4.77.16

Kappa value

  

Negative

Positive

Total

 

Membrane

    

0.426 (p < 0.001)

HFR1

Negative

273

28

301

 
 

Positive

10

18

28

 
 

Total

283

46

329

 

Cytoplasmic

    

0.351 (p < 0.001)

HFR1

Negative

41

15

56

 
 

Positive

68

205

273

 
 

Total

109

220

329

 

Nuclear

    

0.051 (p < 0.018)

HFR1

Negative

21

3

24

 
 

Positive

194

111

305

 
 

Total

215

114

329

 
  1. Chi-square where numbers of cases negative or positive for each antibody at the membrane, cytoplasm or nucleus are shown using cut offs defined in the text. Cohen's Kappa value measures the agreement between the two antibodies, where a value of 1 indicates perfect agreement and a value of 0 indicates agreement is no better than chance.
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Breast Cancer Research

ISSN: 1465-542X

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