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Figure 5 | Breast Cancer Research

Figure 5

From: Type I insulin-like growth factor receptor over-expression induces proliferation and anti-apoptotic signaling in a three-dimensional culture model of breast epithelial cells

Figure 5

Induction of Akt signaling in IGFIR structures. Equatorial confocal sections of 34-day control (pCLXSN, panels a, c) and IGFIR acinar structures (panels c, d) labeled with phosphospecific antibodies to Akt- [S473] (green; panels a, b) and mammalian target of rapamycin (mTOR)- [S2448] (green; panels c, d) and the nuclear counterstain TO-PRO-3 (blue). Scale bars = 50 μm.

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