Table 6 Therapeutic and spontaneous abortions among BRCA1 and BRCA2 mutations carriers
From: Spontaneous and therapeutic abortions and the risk of breast cancer among BRCAmutation carriers
Cases | Controls | OR (95% CI) | P value | |
|---|---|---|---|---|
BRCA1 carriers | ||||
Neither | 887 | 888 | 1 | |
Therapeutic only | 135 | 144 | 0.98 (0.74–1.26) | 0.82 |
Spontaneous only | 233 | 221 | 1.09 (0.87–1.35) | 0.46 |
Either | 368 | 365 | 1.04 (0.87–1.59) | 0.69 |
Both | 57 | 58 | 1.06 (0.71–1.59) | 0.78 |
BRCA2 carriers | ||||
Neither | 253 | 216 | 1 | |
Therapeutic only | 42 | 50 | 0.68 (0.42–1.11) | 0.12 |
Spontaneous only | 76 | 92 | 0.78 (0.55–1.11) | 0.16 |
Either | 118 | 142 | 0.75 (0.55–1.02) | 0.06 |
Both | 9 | 22 | 0.36 (0.14–0.88) | 0.02 |