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Table 1 Comparison of spontaneous abortions among BRCA mutation carriers and non-carriers

From: Spontaneous and therapeutic abortions and the risk of breast cancer among BRCAmutation carriers

 

All carriers

BRCA1

BRCA2

Non-carriers

Age (mean)

49.7

48.8

51.3

46.7

Year of birth (mean)

1950

1951

1948

1951

Number of full-term pregnancies

2.38

2.36

2.42

2.43

Number of spontaneous abortions

    

   Never

2,103 (73.9%)

1,404 (74.8%)

688 (72.4%)

478 (72.8%)

   Ever

743 (26.1%)

474 (25.2%)

262 (27.6%)

179 (27.2%)

1

527 (18.5%)

332 (17.7%)

189 (19.9%)

134 (20.4%)

2

145 (5.1%)

95 (5.0%)

49 (5.2%)

30 (5.0%)

3+

71 (2.5%)

47 (2.5%)

24 (2.5%)

15 (2.3%)

   Mean

0.38

0.37

0.40

0.38

  1. Eighteen subjects had a mutation in both BRCA1 and BRCA2.