Analysis of cancer risk and BRCA1 and BRCA2mutation prevalence in the kConFab familial breast cancer resource

Breast Cancer Research

Table 8 Haplotype sharing in BRCA1/2 mutation negative^a families

Family type	BRCA1 haplotype shared^b	BRCA2 haplotype shared^b	BRCA1 and BRCA2 haplotype shared	Neither BRCA1 nor BRCA2 shared	Total
Female breast cancer only	13	10	10	46	79
Female breast and ovarian cancer	11	3	0	15	29
Ovarian cancer only	0	0	0	0	0
Female and male breast cancer	1	2	1	3	7
Female and male breast cancer and ovarian cancer	0	0	0	4	4
Male breast cancer only	0	0	0	0	0
Total	25	15	11	68	119

^aIndex cases screened by high-sensitivity methods. ^bAll cases from families on whom at least three blood samples were available from cases affected by breast or ovarian cancer share alleles at all markers tested.

ISSN: 1465-542X