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Table 2 Conditional logistic regression models examining XRCC1 polymorphisms and postmenopausal breast cancer stratified by smoking status.

From: A prospective study of XRCC1(X-ray cross-complementing group 1) polymorphisms and breast cancer risk

Polymorphism Never smokers Ever smokers
Arg194Trp
   Arg/Arg
No. of cases/no. of controls 217/237 216/175
ORa (95% CI) 1.00 (ref.) 1.00 (ref.)
   Arg/Trp or Trp/Trp
No. of cases/no. of controls 26/36 21/32
ORa (95% CI) 0.78 (0.43–1.40) 0.47 (0.24–0.94)
  Interaction p = 0.28
Arg399Gln
   Arg/Arg
No. of cases/no. of controls 107/104 88/88
ORa (95% CI) 1.00 (ref.) 1.00 (ref.)
   Arg/Gln
No. of cases/no. of controls 100/112 92/89
ORa (95% CI) 0.91 (0.57–1.43) 1.06 (0.66–1.72)
   Gln/Gln
No. of cases/no. of controls 23/35 38/20
ORa (95% CI) 0.64 (0.33–1.26) 2.76 (1.36–5.63)
  Interaction p = 0.01
  1. aMultivariate odds ratio and corresponding 95% confidence interval adjusted for: matched pairs, body mass index, age at menopause, age at menarche, alcohol intake, education, parity, age at first live birth, physical activity, history of breast cysts, family history of breast cancer in mother or sister, use of hormone replacement therapy, and smoking status. XRCC1, X-ray cross-complementing group 1.