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Table 1 Conditional logistic regression models examining the association between XRCC1 polymorphisms and postmenopausal breast cancer risk

From: A prospective study of XRCC1(X-ray cross-complementing group 1) polymorphisms and breast cancer risk

Polymorphism No. of cases No. of controls OR (95% CI)a OR (95% CI)b
Arg194Trp (485 pairs)
   Arg/Arg 437 415 1.00 (reference) 1.00 (reference)
   Arg/Trp or Trp/Trpc 48 70 0.66 (0.45–0.97) 0.62 (0.40–0.95)
Arg399Gln (452 pairs)
   Arg/Arg 196 194 1.00 (reference) 1.00 (reference)
   Arg/Gln 195 202 0.95 (0.71–1.27) 1.01 (0.73–1.39)
   Gln/Gln 61 56 1.08 (0.71–1.63) 1.27 (0.79–2.02)
   Arg/Gln or Gln/Gln 256 258 0.98 (0.75–1.28) 1.06 (0.78–1.44)
  1. aOdds ratio and corresponding 95% confidence interval adjusted for matched pairs; bmultivariate odds ratio and corresponding 95% confidence interval adjusted for: matched pairs, body mass index, age at menopause, age at menarche, alcohol intake, education, parity, age at first live birth, physical activity, history of breast cysts, family history of breast cancer in mother or sister, use of hormone replacement therapy, and smoking status; chomozygote TT group = one case and two controls. XRCC1, X-ray cross-complementing group 1.