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Table 3 Downregulated genes in MCF-7 cells after exposure to rapamycin plus CN-A for 12 hours

From: Effects of combined treatment with rapamycin and cotylenin A, a novel differentiation-inducing agent, on human breast carcinoma MCF-7 cells and xenografts

   Gene expression ratio
GenBank number Gene name Rapamycin + CN-A Rapamycin CN-A
XM_097230.3 Similar to Cerebellin-like glycoprotein 1 (LOC147381) 0.15 0.93 0.22
NM_006417.2 Interferon-induced protein 44 (IFI44) 0.18 0.62 0.24
XM_095568.5 Hypothetical protein DKFZp762C1112 (DKFZp762C1112) 0.19 1.13 0.29
NM_006820.1 Chromosome 1 open reading frame 29 (C1orf29) 0.20 0.83 0.21
NM_004430.1 Early growth response 3 (EGR3) 0.21 0.53 0.19
NM_024563.1 Hypothetical protein FLJ14054 (FLJ14054) 0.22 0.52 0.45
NM_017816.1 Hypothetical protein FLJ20425 (LYAR) 0.28 0.44 0.45
NM_004934.2 Cadherin 18, type 2 (CDH18) 0.28 1.10 0.20
NM_152454.1 Hypothetical protein FLJ31461 (FLJ31461) 0.29 1.11 0.29
XM_084501.3 Hypothetical protein LOC143381 (LOC143381) 0.29 1.36 0.24
NM_004704.1 RNA, U3 small nucleolar interacting protein 2 (RNU3IP2) 0.30 0.61 0.65
NM_006993.1 Nucleophosmin/nucleoplasmin, 3 (NPM3) 0.32 0.48 0.47
NM_003504.2 CDC45 cell division cycle 45-like (S. cerevisiae) (CDC45L) 0.32 0.48 0.69
XM_059689.2 Similar to agCP15329 (LOC134111) 0.34 0.69 0.38
NM_015179.1 KIAA0690 protein (KIAA0690) 0.35 0.56 0.71
NM_014520.1 MYB binding protein (P160) 1a (MYBBP1A) 0.35 0.53 0.62
XM_300777.1 Similar to muscle protein (LOC348523) 0.35 0.70 0.69
NM_032509.1 RNA binding protein (LOC84549) 0.35 0.47 0.75
NM_014503.1 Downregulated in metastasis (DRIM) 0.36 0.48 0.56
NM_000269.1 Nonmetastatic cells 1, protein (NM23A) expressed in (NME1) 0.37 0.58 0.65
XM_050219.6 Synaptopodin 2 (SYNPO2) 0.37 0.93 0.57
XM_295865.1 LOC340895 (LOC340895) 0.37 1.34 0.33
NM_133263.1 PPAR gamma coactivator 1β(PERC) 0.37 0.62 0.74
NM_002220.1 Inositol 1,4,5-trisphosphate 3-kinase A (ITPKA) 0.37 0.60 0.62
NM_015068.1 Oaternally expressed 10 (PEG10) 0.38 0.77 0.43
  1. CN-A, cotylenin A.