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Table 5 Comparison of ESEfinder and Rescue-ESE programs for identification of potential ESEs in exons 2–10 of the BRCA1 gene

From: Evolutionary conservation analysis increases the colocalization of predicted exonic splicing enhancers in the BRCA1gene with missense sequence changes and in-frame deletions, but not polymorphisms

  ESEs predicted by ESEfinder ESEs predicted by Rescue-ESE ESEs predicted by both programs Proportion of ESEfinder predicted ESEs also detected by Rescue-ESE
BRCA1 exons 2–10 (total) 47 116 11 23%
BRCA1 exons 2–10 (conserved or shared ESEs between human and mouse) 20 69 9 45%
BRCA1 exons 2–10 (conserved or shared ESEs between human and mouse affected by breast cancer associated sequence changes) 16 16 3 19%