Prognostic factors | Cut-off points | Intensity of staining (p-value) | Percentage of positive cells (p-value) |
---|---|---|---|
Age (years; median 56) | <40, 41–50, 51–60, >60 | 0.011 | 0.014 |
Menopausal status | Pre- or post-menopausal | 0.547 | 0.917 |
Histological grade | Well, moderate, poor differentiated | 0.009 | <0.001 |
Lymph node (LN) stage | LN -/ LN+ | 0.368 | 0.419 |
Tumour size (mm) | <10, 11–20, 21–30, 31–40, 41–50 | 0.594 | 0.884 |
Nottingham Prognostic Index | Good, moderate, or poor | 0.151 | 0.016 |
Tumour type | 1, 2, 3 or 4 | 0.093 | 0.007 |
Vascular invasion | None or definite | 0.293 | 0.316 |
Distant metastases | Absent or present | 0.515 | 0.532 |
Any recurrence | Absent or present | 0.533 | 0.743 |
Local recurrence | Absent or present | 0.775 | 0.908 |
Regional recurrence | Absent or present | 0.314 | 0.278 |