High expression of Lewisy/bantigens is associated with decreased survival in lymph node negative breast carcinomas

Table 1 Patient and tumour characteristics

Tumour and patient characteristics	Proportion
Alive	86% (570)
Dead (of breast cancer)	14% (90)
Age (years)
<40	9%(58)
41–50	29%(192)
51–60	33% (221)
>61	29% (189)
Menopausal status^a
Premenopausal	36% (227/623)
Postmenopausal	64% (396/623)
Histological grade
Grade 1	20% (135)
Grade 2	33% (215)
Grade 3	47% (310)
Lymph node status
Negative	65% (427)
Positive	35% (233)
Nottingham Prognostic Index^a
Good	35%(226/638)
Moderate	52%(332/638)
Poor	13%(80/632)
Tumour histological type^b
Group 1	5% (32/647)
Group 2	22% (142/647)
Group 3	12% (78/647)
Group 4	61% (395/647)
Vascular invasion^a
None or probable	69% (444/643)
Definite	31% (199/643)
Distant metastases
Absent	85%(559)
Present	15% (101)
Any recurrence
Absent	74% (488)
Present	26% (172)
Regional recurrence (axillary lymph node)
Absent	91% (598)
Present	9% (62)
Local recurrence (in the breast)
Absent	90% (591)
Present	10% (69)

^aPercentage of total number of recorded cases. ^bTumour sections were classified into four prognostic type groups as previously described [26]: 1, excellent prognosis type (>80% 10 year survival) includes tubulo-lobular, tubular, mucinous and invasive cribriform carcinoma; 2, good types (60% to 80% 10 year survival) includes tubular mixed, mixed ductal with special type and alveolar lobular carcinoma; 3, moderate prognosis types (50% to 60% 10 year survival) includes classical lobular, medullary, atypical medullary and lobular mixed carcinoma; 4, poor prognosis types (≤ 50% 10 year survival) includes ductal/NST, solid lobular, mixed ductal and lobular carcinoma.

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