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Table 2 Distribution of cells in the different cell cycle phases (%) and apoptotic cells (%) after different treatments

From: Addition of 5-fluorouracil to doxorubicin-paclitaxel sequence increases caspase-dependent apoptosis in breast cancer cell lines

  MCF-7 BRC-230
Treatment G1 S G2-M Apoptosis G1 S G2-M Apoptosis
Untreated cells 48 40 12 1 55 33 12 2
Dox→Pacl 6a 14a 80a 22a 10a 27a 63a 15a
Dox→Pacl→48-h washout 3a 16a 81a 17a 5a 11a 84a 15a
Dox→Pacl→48-h washout→5-FU 15a 49 36a 40a 20a 42a 38a 37a
  1. aP < 0.05 by t-test. 5-FU, 5-fluorouracil; Dox, doxorubicin; Pacl, paclitaxel.