Breast Cancer Research

Table 2 Distribution of cells in the different cell cycle phases (%) and apoptotic cells (%) after different treatments

From: Addition of 5-fluorouracil to doxorubicin-paclitaxel sequence increases caspase-dependent apoptosis in breast cancer cell lines

	MCF-7				BRC-230
Treatment	G1	S	G2-M	Apoptosis	G1	S	G2-M	Apoptosis
Untreated cells	48	40	12	1	55	33	12	2
Dox→Pacl	6^a	14^a	80^a	22^a	10^a	27^a	63^a	15^a
Dox→Pacl→48-h washout	3^a	16^a	81^a	17^a	5^a	11^a	84^a	15^a
Dox→Pacl→48-h washout→5-FU	15^a	49	36^a	40^a	20^a	42^a	38^a	37^a

^aP < 0.05 by t-test. 5-FU, 5-fluorouracil; Dox, doxorubicin; Pacl, paclitaxel.

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