From: The membrane cytoskeletal crosslinker ezrin is required for metastasis of breast carcinoma cells
Cell linea | Transfected with | Primary tumour takes (%) | Day of 1 cm tumour diameterb | Day of sacrifice | Metastasis (%)c |
---|---|---|---|---|---|
SP1 | None | 100% (13/13) | 24 ± 7 | 35 | 23% (3/13) |
AC2M2 | None | 100% (11/11) | 30 ± 5 | 41 | 90% (10/11)†|
pCB6 | Vector | 100% (8/8) | 33 ± 4 | 39 | 88% (7/8) |
WTC4 | WT ezrin | 100% (7/7) | 28 ± 4 | 41 | 88% (6/7) |
WTC6 | WT ezrin | 100% (15/15) | 26 ± 2 | 39 | 87% (13/15) |
NTC6 | N-term ezrin | 38% (3/8) | 40 ± 10* | 47 | 0% (0/8)‡ |
NTC7 | N-term ezrin | 100% (8/8) | 28 ± 1 | 39 | 38% (3/8)‡ |
NTB8d | N-term ezrin | 100% (5/5) | 29 ± 3 | 41 | 0% (0/5)‡ |