Table 5 Receiver operating characteristic curve analysis of individual parameters for differential diagnosis
Malignant vs. Benign | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
|  | ADC (×10− 3 mm2/s) | Dt (×10− 3 mm2/s) | Dp (mm2/s) | f | C1 | C2 | C3 | C1C2 | F1 | F2 | F3 | F1F2 |
AUC | 0.853 | 0.804 | 0.643 | 0.634 | 0.833 | 0.513 | 0.647 | 0.767 | 0.871 | 0.663 | 0.714 | 0.851 |
Threshold | ≤ 1.025 | ≤ 0.729 | >0.022 | ≤ 0.255 | >0.343 | ≤ 2.900 | ≤ 0.227 | >0.503 | >0.124 | ≤ 0.780 | ≤ 0.106 | >0.123 |
Sensitivity (%) | 75.00 | 78.45 | 49.14 | 75.86 | 80.17 | 89.66 | 84.48 | 75.86 | 96.55 | 87.93 | 81.90 | 81.03 |
Specificity (%) | 82.93 | 75.61 | 78.05 | 51.22 | 70.73 | 24.39 | 48.78 | 70.73 | 65.85 | 51.22 | 58.54 | 80.49 |
Malignant vs. Healthy | ||||||||||||
|  | ADC (×10− 3 mm2/s) | Dt (×10− 3 mm2/s) | Dp (mm2/s) | f | C1 | C2 | C3 | C1C2 | F1 | F2 | F3 | F1F2 |
AUC | 0.793 | 0.646 | 0.610 | 0.644 | 0.968 | 0.871 | 0.695 | 0.982 | 0.628 | 0.792 | 0.943 | 0.751 |
Threshold | ≤ 1.162 | ≤ 0.791 | ≤ 0.023 | >0.234 | >0.281 | >1.197 | ≤ 0.126 | >0.330 | >0.124 | >0.696 | ≤ 0.129 | >0.116 |
Sensitivity (%) | 91.38 | 90.52 | 60.34 | 54.31 | 88.79 | 82.76 | 55.17 | 87.07 | 96.55 | 82.76 | 93.97 | 84.48 |
Specificity (%) | 66.88 | 54.14 | 59.87 | 68.79 | 91.08 | 79.62 | 78.34 | 99.36 | 44.59 | 64.33 | 78.34 | 61.78 |
Benign vs. Healthy | ||||||||||||
|  | ADC (×10− 3 mm2/s) | Dt (×10− 3 mm2/s) | Dp (mm2/s) | f | C1 | C2 | C3 | C1C2 | F1 | F2 | F3 | F1F2 |
AUC | 0.511 | 0.557 | 0.746 | 0.737 | 0.660 | 0.863 | 0.502 | 0.798 | 0.658 | 0.840 | 0.699 | 0.586 |
Threshold | ≤ 1.388 | >0.472 | ≤ 0.022 | >0.225 | >0.302 | >0.999 | >0.100 | >0.330 | ≤ 0.196 | >0.699 | ≤ 0.140 | ≤ 0.147 |
Sensitivity (%) | 63.41 | 100 | 78.05 | 80.49 | 39.02 | 90.24 | 65.85 | 51.22 | 90.24 | 87.80 | 65.85 | 90.24 |
Specificity (%) | 52.23 | 21.66 | 65.61 | 58.60 | 94.27 | 66.88 | 11.46 | 99.36 | 38.22 | 64.97 | 75.16 | 27.39 |