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Table 1 Integrin gene expressions with significant difference in TAMR and ADR cells compared to MCF-7 cells

From: siRNA treatment targeting integrin α11 overexpressed via EZH2-driven axis inhibits drug-resistant breast cancer progression

 

TAMR

ADR

Fold Changea)

P-Value

Fold Changea)

P-Value

ITGA11

665.23

0.0004

31.47

0.0139

ITGA6

9.87

0.0022

51.68

0.0025

ITGA1

9.24

0.0074

2.95

0.0018

ITGA8

6.48

0.0097

-2.44

0.0173

ITGA5

5.7

0.0327

11.66

0.0069

ITGA7

5.16

0.0052

2.56

0.0399

ITGB8

4.59

0.0223

42.97

0.0014

ITGB3

2.01

0.1919

2.78

0.0731

ITGA9

1.85

0.3860

1.07

0.9092

ITGB2

1.5

0.5898

1.95

0.3875

ITGB7

1.3

0.2244

1.18

0.3891

ITGB1

-2.55

0.006

1.7

0.1330

ITGB6

-4.47

0.0814

-1.47

0.5835

ITGA3

-4.92

0.0211

10.27

0.0190

ITGA2

-12.71

0.0001

-19.8

0.0023

ITGB4

-20.76

0.0216

6.24

0.0307

  1. a) The gene expression level was compared to that of parental MCF-7 cells
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Breast Cancer Research

ISSN: 1465-542X

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